Hydrazine → 6-(N-methylpiperazinyl)hexylamine

HRID 1463818Notes

Reaction equation

HRID 1463818 reaction equation
[NH2:1]N.[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]C1C=CC=C2C(NC(=O)C=12)=O>CO>[CH3:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH:5]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][NH2:1]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 544966336-(N-methylpiperazinyl)hexylphthalimide

Product 1

HCID 537642486-(N-methylpiperazinyl)hexylamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 6-(N-methylpiperazinyl)hexylphthalimide (263 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-da055af6af9e4c54897078cdd4c65a02
Source dataset
uspto-grants-1994_04
Patent number
US05302593

Reaction notes

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