Tetrabutylammonium Fluoride → HCID 131718385, compound

HRID 1463932Notes

Reaction equation

HRID 1463932 reaction equation
[O:1]([CH:9]([C:38]([F:43])([F:42])[CH2:39][CH2:40][CH3:41])[CH2:10][CH2:11][CH2:12][C@H:13]1[C@H:17]([O:18][CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][O:20]2)[CH2:16][C@H:15]([OH:25])[C@@H:14]1[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][C:32]([O:34][CH:35]([CH3:37])[CH3:36])=[O:33])[Si](C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>C1COCC1>[OH:1][CH:9]([C:38]([F:43])([F:42])[CH2:39][CH2:40][CH3:41])[CH2:10][CH2:11][CH2:12][C@H:13]1[C@H:17]([O:18][CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][O:20]2)[CH2:16][C@H:15]([OH:25])[C@@H:14]1[CH2:26]/[CH:27]=[CH:28]\[CH2:29][CH2:30][CH2:31][C:32]([O:34][CH:35]([CH3:37])[CH3:36])=[O:33]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 131718386HCID 131718386, compound

Product 1

HCID 131718385HCID 131718385, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution of the compound (17) (1.lg) in THF was added tetrabutylammonium fluoride (1M THF, 5.5 ml). The resultant mixture was stirred for 1 hour and 20 minutes. The product obtained after the usual work-up was subjected to silicagel column chromatography to give the titled compound (18).

Workup

  1. customThe product obtained after the usual work-up

Sources & evidence

ORD record
ord-8d0724d2beec4d329531574a9e046e0f
Source dataset
uspto-grants-1994_04
Patent number
US05302617

Reaction notes

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