HRID1463945

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7656

Dibenzylamine

C14H15N

结构：CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC[C@H](C(=O)O)[C@@]3(C)CC[C@@H]12

HCID22812150

未命名化合物

PRODUCTS

生成物

结构：CN1C(=O)CC[C@@]2(C)C1=CC[C@H]1[C@@H]3CC[C@H](C(=O)N(Cc4ccccc4)Cc4ccccc4)[C@@]3(C)CC[C@@H]12

HCID67750918

未命名化合物

收率 74%

PROCEDURE

实验过程

The title compound was prepared in a yield of 74% in a similar manner to that described in Example 1 by reacting 4-methyl-3-oxo-4-azaandrost-5-ene-17β-carboxylic acid (prepared as described in Preparation 5) and N,N-dibenzylamine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-eabfd537d0ef477da9a7739260fb2a41
来源数据集: uspto-grants-1994_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05302621
来源说明: uspto-grants-1994_04

反应 SMILES

[CH3:1][N:2]1[C:19](=[O:20])[CH2:18][CH2:17][C@@:16]2([CH3:21])[C:3]1=[CH:4][CH2:5][C@@H:6]1[C@@H:15]2[CH2:14][CH2:13][C@@:11]2([CH3:12])[C@H:7]1[CH2:8][CH2:9][C@@H:10]2[C:22](O)=[O:23].[CH2:25]([NH:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1>>[CH2:33]([N:32]([CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:22]([C@H:10]1[CH2:9][CH2:8][C@H:7]2[C@H:6]3[C@H:15]([CH2:14][CH2:13][C@:11]12[CH3:12])[C@:16]1([CH3:21])[C:3]([N:2]([CH3:1])[C:19](=[O:20])[CH2:18][CH2:17]1)=[CH:4][CH2:5]3)=[O:23])[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1