Piperidinocarbonitrile → HCID 178492304, compound

Participants

Reaction Steps

2-Amino-5-methoxybiphenyl hydrochloride (0.9 g) was heated with N-cyanopiperidine (0.45 g) in m-cresol (1 ml) at 140° C. for 8 hours to give N-(5-methoxy-2-biphenylyl)piperidine-1-carboxamidine which was crystallised from a 1:9 mixture of ethylacetate and hexane to furnish N-(5-methoxy-2-biphenylyl)piperidine-1-carboxamidine as a pale brown crystals (m.p. 155° C.).

Provenance & Evidence