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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464045Generated: October 30, 2026

M-Cresol → HCID 178424491, compound

https://huagongshe.com/reaction/1464045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
ReactantPiperidinocarbonitrileHCID 73736—
Reactant2-Amino-3'-methylbiphenyl hydrochlorideHCID 2759823—
ProductHCID 178424491HCID 178424491—

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture of 2-amino-3'-methylbiphenyl hydrochloride (1.09 g), N-cyanopiperidine (0.6 g) and m-cresol (0.5 ml) was heated at 100° C. for 3 hours to give N-(3'-methyl-2-biphenylyl)piperidine-1-carboxamidine (m.p. 131° C.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05302720
Source datasetuspto-grants-1994_04
ORD IDord-c09cecaf36a44cbb812e43539fadb088
Source noteuspto-grants-1994_04