反应详情

A mixture of 2-amino-4'-methanesulphonylbiphenyl hydrochloride (2.3 g), N-cyanopiperidine (1.3 g) and m-cresol (10 ml) was heated at 90°-95° C. for 10 hours to give N-(4'-methanesulphonyl-2-biphenylyl)piperidine-1-carboxamidine (m.p. 128°-129° C.) which was recrystallised from hexane.

1. temperaturewas heated at 90°-95° C. for 10 hours