Dimethylcyanamide → HCID 178424488, compound

HRID 1464054Notes

Reaction equation

HRID 1464054 reaction equation
Cl.[NH2:2][C:3]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:4]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[CH3:16][N:17]([CH3:20])[C:18]#[N:19]>C1C(O)=CC=CC=1C>[CH3:16][N:17]([CH3:20])[C:18]([NH:2][C:3]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:4]=1[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[NH:19]

Participants

4

Reactant 2

HCID 15112DimethylcyanamideHCID 19089292HCID 19089292, compound

Product 1

HCID 178424488HCID 178424488, compound

Reagents, catalysts & solvents 1

HCID 342M-CresolSolvent

Procedure

A mixture of 2-amino-3-methylbiphenyl hydrochloride (2.65 g), N,N-dimethylcyanamide (1.3 g) and m-cresol (20 ml) was heated at 90°-95° C. for 18 hours to give N,N-dimethyl-N'-(3-methyl-2-biphenylyl)guanidine as a colourless solid (m.p. 144°-145° C.) which was recrystallised from hexane.

Workup

  1. temperaturewas heated at 90°-95° C. for 18 hours

Sources & evidence

ORD record
ord-8c875439d9294bd7876d00cd9c123e4d
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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