3'-Methylthio-2-nitrobiphenyl → 2-Amino-3'-methylthiobiphenyl

HRID 1464066Notes

Reaction equation

HRID 1464066 reaction equation
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[N+:15]([O-])=O)[CH:6]=[CH:7][CH:8]=1>C(O)C>[NH2:15][C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=1[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([S:2][CH3:1])[CH:4]=1

Participants

3

Reactant 1

HCID 190892373'-Methylthio-2-nitrobiphenyl

Product 1

HCID 190892692-Amino-3'-methylthiobiphenyl

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3'-Methylthio-2-nitrobiphenyl (8 g) was heated at 90°-95° C. for 5 hours with hydrated sodium sulphide (15.6 g) and ethanol (200 ml) to give 2-amino-3'-methylthiobiphenyl (m.p. 114°-115° C.) as a brown oil which was converted into its hydrochloride salt.

Sources & evidence

ORD record
ord-dbede0d520eb45cca9c8ea4427d38c0d
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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