HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexane → 1-(Methylsulfonyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | 1-Benzyl-4-methanesulfonyl-piperazine | HCID 779507 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-(Methylsulfonyl)piperazine | HCID 709161 | — |
Reaction Steps
A mixture of N-benzyl-N'-methanesulphonylpiperazine (12.4 g), cyclohexane (5.1 ml), 10% Pd/C (2 g) and methanol (120 ml) was heated under reflux for 7 hours to give 1-methanesulphonylpiperazine (m.p. 90°-91° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302720 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-3f1cb1df16204e3ca7d776d4c57c6e9f |
| Source note | uspto-grants-1994_04 |