Benzoyl isothiocyanate → HCID 19089216, compound

HRID 1464092Notes

Reaction equation

HRID 1464092 reaction equation
[C:1]([N:9]=[C:10]=[S:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([S:25]([CH3:28])(=[O:27])=[O:26])[CH:20]=1>ClCCl>[C:1]([NH:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([S:25]([CH3:28])(=[O:27])=[O:26])[CH:20]=1)=[S:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 68284Benzoyl isothiocyanateHCID 19089296HCID 19089296, compound

Product 1

HCID 19089216HCID 19089216, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of benzoylisothiocyanate (4 g), 2-amino-3'-methanesulphonylbiphenyl (6.1 g) and dichloromethane (30 ml) at ambient temperature for two hours gave N-benzoyl-N'-(3'-methanesulphonyl-2-biphenylyl)thiourea (m.p. 179°-180° C.).

Sources & evidence

ORD record
ord-dcd7bfcb4ff04839b3ea7ab4fdc36199
Source dataset
uspto-grants-1994_04
Patent number
US05302720

Reaction notes

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