HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl isothiocyanate → N-benzoyl-N'-(4'-fluoro-2-biphenylyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | 4'-Fluoro(1,1'-biphenyl)-2-amine | HCID 2758975 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-benzoyl-N'-(4'-fluoro-2-biphenylyl)thiourea | HCID 15175510 | — |
Reaction Steps
A mixture of 2-amino-4'-fluorobiphenyl (1.5 g) and benzoylisothiocyanate (1.3 g) in dichloromethane (20 ml) was heated under reflux for 6 hours to yield N-benzoyl-N'-(4'-fluoro-2-biphenylyl)thiourea as a colourless solid (m.p. 123°-124° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302720 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-895e4a33b77141418daa291b1570a39e |
| Source note | uspto-grants-1994_04 |