Hydrochloric Acid → HCID 15669333, compound

HRID 1464128Notes

Reaction equation

HRID 1464128 reaction equation
[CH3:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[S:7]([NH2:10])(=[O:9])=[O:8].[OH-].[Na+].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]=[C:21]=[O:22])=[CH:16][CH:15]=1.Cl>CC(C)=O>[CH3:1][C:2]1[CH:6]=[CH:5][S:4][C:3]=1[S:7]([NH:10][C:21]([NH:20][C:17]1[CH:18]=[CH:19][C:14]([Cl:13])=[CH:15][CH:16]=1)=[O:22])(=[O:9])=[O:8]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 76934-Chlorophenyl IsocyanateHCID 14798Sodium HydroxideHCID 3410833-Methylthiophene-2-sulfonamide

Product 1

HCID 15669333HCID 15669333, compoundYield 57.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The procedure of Example 4B was followed with the 3-methyl-2-thiophenesulfonamide (1.6 g, 9.0 mmole), 1N NaOH (9.0 ml), acetone (10 ml), 4-chlorophenyl isocyanate (1.4 g, 9.2 mmole), 1N HCl (9.5 ml) to provide the named product (1.7 g).

Sources & evidence

ORD record
ord-a15941da6d1748cf9d7a3e3c6605614b
Source dataset
uspto-grants-1994_04
Patent number
US05302724

Reaction notes

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