HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenyl Isocyanate → N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Thiophene-3-sulfonamide | HCID 1201388 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide | HCID 19089334 | 73.5% |
Reaction Steps
Procedure of Example 4B was followed with 3-thiophenesulfonamide (1.1 g, 6.81 mmole), acetone (10 ml), 1N NaOH (6.8 ml), 4-chlorophenyl isocyanate (1.05 g, 6.8 mmole) in acetone (10 ml), 1N HCl (8 ml) to give the N-[[(4-chlorophenyl)amino]carbonyl]-3-thiophenesulfonamide (1.44 g, 4 5 mmole).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302724 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-206a8166634a49178131cce9c5494cf5 |
| Source note | uspto-grants-1994_04 |