HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 2-Hydroxy-5-[2-[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]ethenyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | Isobutyl 2-hydroxy-5-[2-[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]ethenyl]benzoate | HCID 54356729 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Hydroxy-5-[2-[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]ethenyl]benzoic acid | HCID 54409484 | — |
Reaction Steps
The product from Example 12c (78 g) was added to a solution of potassium hydroxide (50 g, 0.78 mol) in water (600 mi) and the mixture was refluxed overnight. After addition of activated carbon (2 g) and sodium sulfite (0.5 g) the mixture was allowed to cool, with s&%g to room temperature and then filtered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302718 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-6aa438f45db143c99ef1cb234ebb90f5 |
| Source note | uspto-grants-1994_04 |