HRID1464176

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

结构：Cc1cccnc1NS(=O)(=O)c1ccc(C#Cc2ccc(O)c(C(=O)O)c2)cc1

HCID3086668

Susalimod

C21H16N2O5S

PRODUCTS

生成物

结构：Cc1cccnc1NS(=O)(=O)c1ccc(CC(=O)c2ccc(O)c(C(=O)O)c2)cc1

HCID19423409

未命名化合物

收率 71%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID284

Formic acid

CH2O2

PROCEDURE

实验过程

A solution of 2-hydroxy-5-[[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]ethynyl]benzoic acid (4.1 g, 0.01 mol) in formic acid (100 ml) was refluxed for 30 h. Water (200 ml) was added and the product crystallized to yield 3.0 g (71%) product.

WORKUP

后处理

customthe product crystallized