HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Hydroxy-5-[[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]acetyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Susalimod | HCID 3086668 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2-Hydroxy-5-[[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]acetyl]benzoic acid | HCID 19423409 | 71% |
Reaction Steps
A solution of 2-hydroxy-5-[[4-[(3-methyl-2-pyridinylamino)sulfonyl]phenyl]ethynyl]benzoic acid (4.1 g, 0.01 mol) in formic acid (100 ml) was refluxed for 30 h. Water (200 ml) was added and the product crystallized to yield 3.0 g (71%) product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05302718 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-fc3c761f3bd5494ba498bc57715fcaf6 |
| Source note | uspto-grants-1994_04 |