Water → 2-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)thiazole

HRID 146420Notes

Reaction equation

HRID 146420 reaction equation
[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27].[OH2:21].[S:17]([Cl:18])([Cl:19])=[O:20].[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1.[s:1]1[c:2]([C:6]2([OH:16])[CH2:7][CH2:8][C:9]3([O:10][CH2:11][CH2:12][O:13]3)[CH2:14][CH2:15]2)[n:3][cH:4][cH:5]1>>[s:1]1[c:2]([C:6]2=[CH:7][CH2:8][C:9]3([O:10][CH2:11][CH2:12][O:13]3)[CH2:14][CH2:15]2)[n:3][cH:4][cH:5]1

Participants

6

Reactant 5

HCID 962WaterHCID 1049PyridineHCID 8857Ethyl AcetateHCID 24386Thionyl ChlorideHCID 578033298-(1,3-Thiazol-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol

Product 1

HCID 595561422-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)thiazole

Sources & evidence

ORD record
ord-9b786cc16de0451bb7f31e7a5ec9ae42
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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