HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68614786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | {6,8-Dimethoxy-4-[methyl-(1-phenyl-ethyl)-carbamoyl]-isoquinolin-1-ylmethyl}-carbamic acid tert-butyl ester | HCID 68613798 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 68614786 | HCID 68614786 | 97% |
Reaction Steps
As described in example 1, 112 mg of {6,8-dimethoxy-4-[methyl-(1-phenyl-ethyl)-carbamoyl]-isoquinolin-1-ylmethyl}-carbamic acid tert-butyl ester was treated with HCl in EtOAc to give 86 mg (97%) of 1-aminomethyl-6,8-dimethoxy-isoquinoline-4-carboxylic acid methyl-(1-phenyl-ethyl)-amide hydrochloride. MS: APCI (M+H) calc'd for C22H25N3O3+H 380.5; found 380.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732446B1 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-80a57d060dca4adf89e0ac41527bbc53 |
| Source note | uspto-grants-2010_06 |