Acetic Acid → HCID 19087789, compound

HRID 1464371Notes

Reaction equation

HRID 1464371 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[C:9]([O:11][CH3:12])=[O:10])=[CH:4][C:3]=1[CH2:18][C:19](=[CH2:21])[CH3:20].C(O)(=O)C>CO.[Pd]>[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[C:9]([O:11][CH3:12])=[O:10])=[CH:4][C:3]=1[CH2:18][CH:19]([CH3:21])[CH3:20]

Participants

5

Reactant 2

HCID 176Acetic AcidHCID 19087784HCID 19087784, compound

Product 1

HCID 19087789HCID 19087789, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

4 g (0.014 mol) of the compound from Example V are dissolved in 30 ml of methanol and 10 ml of acetic acid and hydrogenated at 5.3 bar using Pd/C as a catalyst. Reaction time: 2.5 h. After filtering off the catalyst, the solvent is evaporated in vacuo and a slightly yellowish oil is obtained.

Workup

  1. customReaction time
  2. custom2.5 h
  3. filtrationAfter filtering off the catalyst
  4. customthe solvent is evaporated in vacuo
  5. customa slightly yellowish oil is obtained

Sources & evidence

ORD record
ord-66e241d1bdb44173a4f185149c2bb8a9
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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