HCID 19087769, compound → HCID 19087766, compound

HRID 1464374Notes

Reaction equation

HRID 1464374 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[C:9]([O:11][CH3:12])=[O:10])=[CH:4][C:3]=1[N+:18]([O-])=O>C(O)C.[Pd]>[NH2:18][C:3]1[CH:4]=[C:5]([CH:8]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[C:9]([O:11][CH3:12])=[O:10])[CH:6]=[CH:7][C:2]=1[OH:1]

Participants

4

Reactant 1

HCID 19087769HCID 19087769, compound

Product 1

HCID 19087766HCID 19087766, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

5.6 g (20 mmol) of the compound from Example XI are hydrogenated at 4 atm. in 100 ml of ethanol with the addition of 0.5 g of palladium/carbon (10% strength). The catalyst is filtered off with suction, the filtrate is concentrated and the residue is further reacted without further purification (quantitative yield).

Workup

  1. filtrationThe catalyst is filtered off with suction
  2. concentrationthe filtrate is concentrated
  3. customthe residue is further reacted without further purification (quantitative yield)

Sources & evidence

ORD record
ord-b6e484a6a5b64c9893df79ea5da5be36
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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