Sodium Hydroxide → HCID 19087804, compound

HRID 1464379Notes

Reaction equation

HRID 1464379 reaction equation
Cl[CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1.[Cl:13][C:14]1[CH:15]=[C:16]([CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH:17]=[CH:18][C:19]=1[OH:20].[OH-].[Na+]>>[Cl:13][C:14]1[CH:15]=[C:16]([CH2:21][C:22]([O:24][CH3:25])=[O:23])[CH:17]=[CH:18][C:19]=1[O:20][CH2:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 203942-(Chloromethyl)quinolineHCID 92625Methyl 3-chloro-4-hydroxyphenylacetate

Product 1

HCID 19087804HCID 19087804, compound

Procedure

The title compound is prepared in analogy to the procedure of Example XIV from 5.3 g (0.03 mol) of 2-chloromethylquinoline, 6 g (0.03 mol) of methyl 3-chloro-4-hydroxyphenylacetate and 1.2 g (0.03 mol) of sodium hydroxide.

Sources & evidence

ORD record
ord-e424ab0a877a403082828feba87034d1
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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