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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464379Generated: November 1, 2026

Sodium Hydroxide → Methyl 2-[3-chloro-4-(quinolin-2-yl-methoxy)phenyl]acetate

https://huagongshe.com/reaction/1464379

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-(Chloromethyl)quinolineHCID 20394—
ReactantMethyl 3-chloro-4-hydroxyphenylacetateHCID 92625—
ProductMethyl 2-[3-chloro-4-(quinolin-2-yl-methoxy)phenyl]acetateHCID 19087804—

Reaction Steps

The title compound is prepared in analogy to the procedure of Example XIV from 5.3 g (0.03 mol) of 2-chloromethylquinoline, 6 g (0.03 mol) of methyl 3-chloro-4-hydroxyphenylacetate and 1.2 g (0.03 mol) of sodium hydroxide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05304563
Source datasetuspto-grants-1994_04
ORD IDord-e424ab0a877a403082828feba87034d1
Source noteuspto-grants-1994_04