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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464382Generated: October 26, 2026

Sodium Hydroxide → Methyl 2-[3-methoxy-4-(quinolin-2-yl-methoxy)phenyl]acetate

https://huagongshe.com/reaction/1464382

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-(Chloromethyl)quinolineHCID 20394—
ReactantMethyl 4-hydroxy-3-methoxyphenylacetateHCID 85214—
ProductMethyl 2-[3-methoxy-4-(quinolin-2-yl-methoxy)phenyl]acetateHCID 19087794—

Reaction Steps

In analogy to the procedure of Example XIV, the title compound is prepared from 16 g (0.082 mol) of methyl 3-methoxy-4-hydroxyphenylacetate, 14.5 g (0.082 mol) of 2-chloromethylquinoline and 3.28 g (0.082 mol) of sodium hydroxide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05304563
Source datasetuspto-grants-1994_04
ORD IDord-f8110b9fe690400ab97000d517150780
Source noteuspto-grants-1994_04