HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → Ethyl 2-[3-trifluoromethylthio-4-(quinolin-2-yl-methoxy)phenyl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(Chloromethyl)quinoline | HCID 20394 | — |
| Reactant | HCID 54018388 | HCID 54018388 | — |
| Product | Ethyl 2-[3-trifluoromethylthio-4-(quinolin-2-yl-methoxy)phenyl]acetate | HCID 19087777 | — |
Reaction Steps
In analogy to the procedure of Example XIV, the title compound is prepared from 10 g (0.036 mol) of ethyl 4-hydroxy-3-trifluoromethylthiophenylacetate, 7.7 g (0.036 mol) of 2-chloromethylquinoline and 2.88 g (0.072 mol) of sodium hydroxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05304563 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-24df1218e3c0406fb3e16941253d524c |
| Source note | uspto-grants-1994_04 |