反应详情

200 mg (0.21 mmol) of the catalyst [P(phenyl)3 ]4Pd are weighed into a 50 ml brown glass flask (flushed with argon) and 2 g (5.2 mmol) of the compound from Example XX and 1.4 ml (5.2 mmol) of Bu3SnCH=CH2 (d=1.086), both dissolved in 10 ml of toluene, are added under argon. The mixture is heated to boiling for 20 hours with stirring in a light-protected apparatus. The solvent is then evaporated in vacuo and the residue is separated by column chromatography (silica gel 60, eluent: toluene/ethyl acetate=4:1).

1. additionare added under argon
2. temperatureThe mixture is heated
3. customThe solvent is then evaporated in vacuo
4. customthe residue is separated by column chromatography (silica gel 60, eluent: toluene/ethyl acetate=4:1)