Sodium Hydroxide → HCID 19087786, compound

HRID 1464398Notes

Reaction equation

HRID 1464398 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])=[CH:4][C:3]=1[C:13](=[O:15])[CH3:14].Cl[CH2:17][C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1.[OH-].[Na+]>>[C:13]([C:3]1[CH:4]=[C:5]([CH2:8][C:9]([O:11][CH3:12])=[O:10])[CH:6]=[CH:7][C:2]=1[O:1][CH2:17][C:18]1[CH:27]=[CH:26][C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[N:19]=1)(=[O:15])[CH3:14]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 203942-(Chloromethyl)quinolineHCID 10560287HCID 10560287, compound

Product 1

HCID 19087786HCID 19087786, compound

Procedure

In analogy to the procedure of Example XIV, the title compound is prepared from 2.9 g (0.014 mol) of the compound from Example VIII, 2.5 g (0.014 mol) of 2-chloromethylquinoline and 0.56 g (0.014 mol) of sodium hydroxide.

Sources & evidence

ORD record
ord-cf15de0fae3f42fea3aa4299c78e584f
Source dataset
uspto-grants-1994_04
Patent number
US05304563

Reaction notes

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