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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464398Generated: October 31, 2026

Sodium Hydroxide → Methyl 2-[3-acetyl-4-(quinolin-2-yl-methoxy)phenyl]acetate

https://huagongshe.com/reaction/1464398

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-(Chloromethyl)quinolineHCID 20394—
ReactantHCID 10560287HCID 10560287—
ProductMethyl 2-[3-acetyl-4-(quinolin-2-yl-methoxy)phenyl]acetateHCID 19087786—

Reaction Steps

In analogy to the procedure of Example XIV, the title compound is prepared from 2.9 g (0.014 mol) of the compound from Example VIII, 2.5 g (0.014 mol) of 2-chloromethylquinoline and 0.56 g (0.014 mol) of sodium hydroxide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05304563
Source datasetuspto-grants-1994_04
ORD IDord-cf15de0fae3f42fea3aa4299c78e584f
Source noteuspto-grants-1994_04