HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(3-Hydroxy-2-fluoro)propylimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 15077085 | HCID 15077085 | — |
| Product | 1-(3-Hydroxy-2-fluoro)propylimidazole | HCID 13435265 | 37.6% |
Reaction Steps
To 910 mg (3.94 mmol) of 1-(2'-fluoro-3'-acetoxypropyl)-2-nitroimidazole, 6N-HCl was added and stirred overnight at room temperature. The reaction mixture was concentrate and subjected to isolation and purification by silica gel column chromatography to give 280 mg of 1-(2'-fluoro-3'-hydroxypropyl)-2-nitroimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05304654 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-6f467fb9eb57416cb9b494e67e25c81c |
| Source note | uspto-grants-1994_04 |