Hydrogen Peroxide → HCID 10979338, compound

HRID 1464563Notes

Reaction equation

HRID 1464563 reaction equation
[OH:1]O.[CH2:3]([S:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[S:17]([NH2:20])(=[O:19])=[O:18])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1>C(O)(=O)C>[CH2:3]([S:10]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[S:17]([NH2:20])(=[O:19])=[O:18])=[O:1])[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 19086754HCID 19086754, compound

Product 1

HCID 10979338HCID 10979338, compoundYield 94.6%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

102 ml of 30% hydrogen peroxide solution are added dropwise at a temperature of +10° C. to a solution of 219 g of 2-benzylthiophenylsulfonamide obtained in accordance with Example P1 in 500 ml of concentrated acetic acid. The reaction mixture is then stirred for 5 hours at a temperature of +25° C., the product slowly crystallising out. After separating off the crystals, washing with water and drying, 219 g (94.6%) of 2-benzylsulfinylphenylsulfonamide are obtained in the form of colourless crystals having a melting point of from +206° to +209° C.

Workup

  1. customthe product slowly crystallising out
  2. customAfter separating off the crystals
  3. washwashing with water
  4. customdrying

Sources & evidence

ORD record
ord-68613d1724a04e4eae0308cad80ef8da
Source dataset
uspto-grants-1994_04
Patent number
US05306693

Reaction notes

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