HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine → Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine | HCID 750 | — |
| Reactant | L-Aspartic Acid | HCID 5960 | — |
| Reactant | L-Tyrosine | HCID 6057 | — |
| Reactant | L-Methionine | HCID 6137 | — |
| Reactant | L-Phenylalanine | HCID 6140 | — |
| Reactant | Anisole | HCID 7519 | — |
| Reactant | Thioanisole | HCID 7520 | — |
| Reactant | 1,2-Ethanedithiol | HCID 10902 | — |
| Reactant | Sincalide | HCID 9833444 | — |
| Product | Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 | HCID 444998 | — |
Reaction Steps
The cleavage yield of CCK-8 peptide, using a similar procedure with scavengers (thioanisole, anisole and 1,2-ethanedithiol) present in the cleavage cocktail, was about 95%. AAA showed a composition of: Asp 2.03, Gly 1.04, Met 1.92, Tyr 0.99, Phe 1.02, which is characteristic of CCK-8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05306562 |
| Source dataset | uspto-grants-1994_04 |
| ORD ID | ord-78eed412d5a6423db2dc1185692fcbc0 |
| Source note | uspto-grants-1994_04 |