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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464623Generated: November 1, 2026

2-Oxobutanoic Acid → L-Aspartic Acid

https://huagongshe.com/reaction/1464623

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxobutanoic AcidHCID 58—
Reactant4-Methyl-2-oxovaleric acidHCID 70—
Reactant2-Oxovaleric acidHCID 74563—
Reactant3-hydroxy-L-aspartic acidHCID 440175—
ProductL-Aspartic AcidHCID 5960—

Reaction Steps

β-hydroxy, aspartic acid derviatives 12b-d were prepared from copperglycinate and 2-oxobutanoic acid, 2-oxopentanoic acid and 4-methyl,2-oxopentanoic acid, respectively, according to the procedure described by L. Benoiton et al. (J. Am. Chem. Soc, 81, 1726-1729, 1959). β-Hydroxyaspartic acid was obtained from Sigma Chem. Comp.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05306809
Source datasetuspto-grants-1994_04
ORD IDord-decc8a782cdc4395a9b7b6cc2b008839
Source noteuspto-grants-1994_04