4-Methoxybenzaldehyde → 5-[(4-Methoxyphenyl)methylene]-3-methyl-2,4-imidazolidinedione

HRID 1464650Notes

Reaction equation

HRID 1464650 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[CH3:11][N:12]1[C:16](=[O:17])[CH2:15][NH:14][C:13]1=[O:18]>>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[C:15]2[NH:14][C:13](=[O:18])[N:12]([CH3:11])[C:16]2=[O:17])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 312444-MethoxybenzaldehydeHCID 1388512,4-Imidazolidinedione, 3-methyl-

Product 1

HCID 44496975-[(4-Methoxyphenyl)methylene]-3-methyl-2,4-imidazolidinedioneYield 41%

Procedure

Prepared according to the procedure described in Example 93 using 4-methoxybenzaldehyde (3.4 g, 25 mmoles) and 3-methyl hydantoin (3.0 g, 21 mmoles). Recrystallization from acetonitrile gave the pure product (2.0 g), mp 221°-222° C.

Workup

  1. customPrepared
  2. customRecrystallization from acetonitrile

Sources & evidence

ORD record
ord-b931620db1204d8599053b374284900c
Source dataset
uspto-grants-1994_04
Patent number
US05306822

Reaction notes

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