Aluminum(III) Chloride → 2-Chloro-1,3,5-trimethylbenzene

HRID 1464709Notes

Reaction equation

HRID 1464709 reaction equation
[Cl-:1].[Al+3].[Cl-].[Cl-].ClC(O[C:9]1[C:14]([CH3:15])=[CH:13][C:12]([CH3:16])=[CH:11][C:10]=1[CH3:17])=O>>[CH3:17][C:10]1[CH:11]=[C:12]([CH3:16])[CH:13]=[C:14]([CH3:15])[C:9]=1[Cl:1]

Participants

3

Reactant 2

HCID 6451240Aluminum(III) ChlorideHCID 11106338HCID 11106338, compound

Product 1

HCID 154622-Chloro-1,3,5-trimethylbenzeneYield 72%

Conditions

Temperature
180 °C

Procedure

0.5 g of anhydrous aluminium chloride was added to 50 g of 2,4,6-trimethylphenyl chloroformate and the mixture was heated at 180° C. for 1.5 hours at normal pressure. The reaction mixture was then cooled and worked up as described in Example 1. 2,4,6-Trimethylchlorobenzene was obtained in a yield of 72%.

Workup

  1. temperatureThe reaction mixture was then cooled

Sources & evidence

ORD record
ord-4fbf6cec25314c99abef0b6483b7377f
Source dataset
uspto-grants-1994_04
Patent number
US05306849

Reaction notes

Loading…