Aluminum(III) Chloride → 2-Chloro-1,3,5-trimethylbenzene

Participants

Role	Name	HCID	Charge
Reactant	Aluminum(III) Chloride	HCID 6451240	—
Reactant	HCID 11106338	HCID 11106338	—
Product	2-Chloro-1,3,5-trimethylbenzene	HCID 15462	72%

Reaction Conditions

Temperature	180 °C

Reaction Steps

0.5 g of anhydrous aluminium chloride was added to 50 g of 2,4,6-trimethylphenyl chloroformate and the mixture was heated at 180° C. for 1.5 hours at normal pressure. The reaction mixture was then cooled and worked up as described in Example 1. 2,4,6-Trimethylchlorobenzene was obtained in a yield of 72%.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05306849
Source dataset	uspto-grants-1994_04
ORD ID	ord-4fbf6cec25314c99abef0b6483b7377f
Source note	uspto-grants-1994_04