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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1464742Generated: October 25, 2026

2-Hepten-4-yne, 1-bromo-6,6-dimethyl- → (E)-N-(6-methoxy-6-methyl-2-hepten-4-ynyl)-5-[3-(3-thienyl)phenoxy]pentylamine

https://huagongshe.com/reaction/1464742

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Hepten-4-yne, 1-bromo-6,6-dimethyl-HCID 11074428—
Reactant(E)-6-methoxy-6-methyl-2-hepten-4-ynyl bromideHCID 13647222—
Reactant5-[3-(3-Thienyl)phenoxy]pentylamineHCID 19916951—
Reactant2-[2-[3-(3-Thienyl)phenoxy]ethoxy]ethylamineHCID 19917006—
Product(E)-N-(6-methoxy-6-methyl-2-hepten-4-ynyl)-5-[3-(3-thienyl)phenoxy]pentylamineHCID 19916981—

Reaction Steps

Compound of Example 53 was obtained by performing the same reaction as in Example 52 except that 2-[2-[3-(3-thienyl)phenoxy]ethoxy]ethylamine and (E)-6,6-dimethyl-2-hepten-4-ynyl bromide were used instead of the starting compounds, 5-[3-(3-thienyl)phenoxy]pentylamine and (E)-6-methoxy-6-methyl-2-hepten-4-ynyl bromide, which were used in the above-mentioned reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05306728
Source datasetuspto-grants-1994_04
ORD IDord-9c66eff8cabf42c4a8e8d327f8fa373a
Source noteuspto-grants-1994_04