Acetic Acid → HCID 19917089, compound

HRID 1464790Notes

Reaction equation

HRID 1464790 reaction equation
[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][O:7][CH2:8][C:9]([O:11]CC)=[O:10])=[CH:2]1.[OH-].[Na+].C(O)(=O)C>C(O)C>[S:1]1[CH:5]=[CH:4][C:3]([CH2:6][O:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:2]1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 14798Sodium HydroxideHCID 19917140HCID 19917140, compound

Product 1

HCID 19917089HCID 19917089, compoundYield 96.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

0.9 g of the resulting ether compound was dissolved in 10 ml of ethanol, and an aqueous solution(10 ml) of 1.44 g of sodium hydroxide was added. The mixture was refluxed for 4 hours, and then acetic acid was added to the solution to acidify it. The solvent was evaporated, and ethyl acetate and water were added. The organic layer separated was worked up in a customary manner to give 0.75 g of the captioned compound as a colorless oil.

Workup

  1. temperatureThe mixture was refluxed for 4 hours
  2. customThe solvent was evaporated
  3. additionethyl acetate and water were added
  4. customThe organic layer separated

Sources & evidence

ORD record
ord-82be9b0547514634a10c0534d211a9a5
Source dataset
uspto-grants-1994_04
Patent number
US05306728

Reaction notes

Loading…