Vinyl chloroformate → HCID 59601719, compound

HRID 1464861Notes

Reaction equation

HRID 1464861 reaction equation
[CH3:1][O:2][NH:3][C:4](=[O:7])[CH:5]=[CH2:6].[CH:8]([O:10][C:11](Cl)=[O:12])=[CH2:9]>>[CH:8]([O:10][C:11](=[O:12])[N:3]([O:2][CH3:1])[C:4](=[O:7])[CH:5]=[CH2:6])=[CH2:9]

Participants

3

Reactant 2

HCID 78808Vinyl chloroformateHCID 13531445N-Methoxyprop-2-enamide

Product 1

HCID 59601719HCID 59601719, compound

Procedure

The synthesis was carried out analogously to synthesis example 8 using N-methoxy-acrylamide and chloroformic acid vinyl ester. Purification by column chromatography on silica gel (PE:EE=9:1) yielded 1.6 g (91% of th.) of the title compound as a colorless liquid.

Workup

  1. customPurification by column chromatography on silica gel (PE:EE=9:1)

Sources & evidence

ORD record
ord-5457b3292eac4bc197a3beacfcc105ba
Source dataset
uspto-grants-2015_04
Patent number
US08999323B2

Reaction notes

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