N-(tert-butoxycarbonyl)glycine → HCID 86686657, compound

HRID 1464966Notes

Reaction equation

HRID 1464966 reaction equation
Cl.Cl.[CH2:3]([O:7][C:8]1[CH:13]=[C:12]([N:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)[N:11]=[CH:10][N:9]=1)[CH:4]([CH3:6])[CH3:5].[C:20]([O:24][C:25]([NH:27][CH2:28][C:29](O)=[O:30])=[O:26])([CH3:23])([CH3:22])[CH3:21]>>[CH2:3]([O:7][C:8]1[N:9]=[CH:10][N:11]=[C:12]([N:14]2[CH2:19][CH2:18][N:17]([C:29](=[O:30])[CH2:28][NH:27][C:25](=[O:26])[O:24][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:16][CH2:15]2)[CH:13]=1)[CH:4]([CH3:6])[CH3:5]

Participants

3

Reactant 2

HCID 78288N-(tert-butoxycarbonyl)glycineHCID 66747984HCID 66747984, compound

Product 1

HCID 86686657HCID 86686657, compound

Procedure

The title compound was prepared according to the procedure described in Example 3 using 4-isobutoxy-6-(piperazin-1-yl)pyrimidine dihydrochloride and 2-((tert-butoxycarbonyl)amino)acetic acid.

Sources & evidence

ORD record
ord-8a6084c1ca724f0b9562ae10c56972c3
Source dataset
uspto-grants-2015_04
Patent number
US08999974B2

Reaction notes

Loading…