5-Amino-2-methylpyridine → HCID 53345319, compound

HRID 1464994Notes

Reaction equation

HRID 1464994 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=2)=[CH:4][C:3]=1[NH:21][C:22]([C:24]1[C:28]2[N:29]=[CH:30][N:31]=[C:32](S(C)=O)[C:27]=2[S:26][CH:25]=1)=[O:23].[CH3:36][C:37]1[N:42]=[CH:41][C:40]([NH2:43])=[CH:39][CH:38]=1>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:20])[NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:18])([F:17])[F:19])[CH:11]=2)=[CH:4][C:3]=1[NH:21][C:22]([C:24]1[C:28]2[N:29]=[CH:30][N:31]=[C:32]([NH:43][C:40]3[CH:41]=[N:42][C:37]([CH3:36])=[CH:38][CH:39]=3)[C:27]=2[S:26][CH:25]=1)=[O:23]

Participants

3

Reactant 2

HCID 2433135-Amino-2-methylpyridineHCID 68263099HCID 68263099, compound

Product 1

HCID 53345319HCID 53345319, compound

Procedure

The procedure of Step 3 of Example 13 was repeated except for using the compound obtained in Step 2 of Example 13 and 6-methylpyridine-3-amine to obtain the title compound (see Table 1).

Sources & evidence

ORD record
ord-aa48f5ef0e584cf6bd8754d5bf1957b6
Source dataset
uspto-grants-2015_04
Patent number
US08999973B2

Reaction notes

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