反应详情

t-Butyl 4-(1-methylpiperidine-4-yloxy)-3-(trifluoromethyl)phenylcarbamate (82 mg, 0.299 mmol) was dissolved in methylene chloride (1 mL), and TFA (1 mL) was added thereto. The reaction mixture was stirred at room temperature for 2 hours and then concentrated. The reaction mixture was diluted with ethylene chloride and washed with sat. NaHCO3 solution. The organic layer was dried with Na2SO4, filtered and concentrated to obtain the title compound (63 mg, 77%) without further purification.

1. concentrationconcentrated
2. additionThe reaction mixture was diluted with ethylene chloride
3. washwashed with sat. NaHCO3 solution
4. dry with materialThe organic layer was dried with Na2SO4
5. filtrationfiltered
6. concentrationconcentrated