反应详情

温度

65 °C

4-Methyl-3-nitroaniline (5.0 g, 32.86 mmol) was dissolved in anhydrous THF (25 mL). t-Butyl bicarbonate (7.5 mL, 32.86 mmol) dissolved in anhydrous THF (25 mL) was added slowly to the reaction mixture, which was stirred at 65° C. for 18 hours. After the reaction was completed the remaining organic solvent was distilled under reduced pressure, and water was added thereto. The resulting yellow solid was filtered and dried to obtain the title compound without further purification.

1. additionwas added slowly to the reaction mixture, which
2. distillationwas distilled under reduced pressure, and water
3. additionwas added
4. filtrationThe resulting yellow solid was filtered
5. customdried