tert-Butyl (4-methyl-3-nitrophenyl)carbamate → 5-(Boc-amino)-2-methylaniline

Participants

Reaction Steps

t-Butyl 4-methyl-3-nitrophenylcarbamate (7.6 g, 30.13 mmol) was dissolved in ethanol (167 mL) and subjected to a reaction under 50 psi H2 gas. The reaction mixture was stirred for 2 hours and then concentrated by filtering with Celite to obtain the title compound without further purification.

Provenance & Evidence