HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(5-amino-2-methylphenyl)-4-(cyclopropylamino)thieno[3,2-d]pyrimidine-7-carboxamide → 4-(Cyclopropylamino)-N-(2-methyl-5-(4-(4-methyl-1H-imidazole-1-yl)-3-(trifluoromethyl)benzoamido)phenyl)thieno[3,2-d]pyrimidine-7-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(5-amino-2-methylphenyl)-4-(cyclopropylamino)thieno[3,2-d]pyrimidine-7-carboxamide | HCID 67360673 | — |
| Reactant | 4-(4-methyl-1H-imidazole-1-yl)-3-(trifluoromethyl)benzoic acid | HCID 68678664 | — |
| Product | 4-(Cyclopropylamino)-N-(2-methyl-5-(4-(4-methyl-1H-imidazole-1-yl)-3-(trifluoromethyl)benzoamido)phenyl)thieno[3,2-d]pyrimidine-7-carboxamide | HCID 67360528 | — |
Reaction Steps
The procedure of Step 5 of Example 1 was repeated except for using N-(5-amino-2-methylphenyl)-4-(cyclopropylamino)thieno[3,2-d]pyrimidine-7-carboxamide and 4-(4-methyl-1H-imidazole-1-yl)-3-(trifluoromethyl)benzoic acid to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999973B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-03b9544da5f7435e8c6c3e5c42ae0f4c |
| Source note | uspto-grants-2015_04 |