1-(2-Bromoethyl)-4-chlorobenzene → HCID 86691514, compound

HRID 1465316Notes

Reaction equation

HRID 1465316 reaction equation
Br[CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([Cl:10])=[CH:6][CH:5]=1.[NH:11]([C:13]1[CH:22]=[CH:21][C:16]([C:17]([O:19]C)=[O:18])=[CH:15][CH:14]=1)N.[CH3:23][N:24]1[CH2:29][CH2:28][C:27](=O)[CH2:26][CH2:25]1>C(N(CC)CC)C>[Cl:10][C:7]1[CH:8]=[CH:9][C:4]([CH2:3][CH2:2][CH:25]2[C:26]3[C:14]4[CH:15]=[C:16]([C:17]([OH:19])=[O:18])[CH:21]=[CH:22][C:13]=4[NH:11][C:27]=3[CH2:28][CH2:29][N:24]2[CH3:23])=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 230291-(2-Bromoethyl)-4-chlorobenzeneHCID 740491-Methyl-4-piperidoneHCID 408928Methyl 4-hydrazinylbenzoate

Product 1

HCID 86691514HCID 86691514, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound is prepared by following Method 8 by using 1-(2-bromoethyl)-4-chlorobenzene, methyl 4-hydrazinobenzoate, triethylamine and N-methyl-4-piperidone

Sources & evidence

ORD record
ord-8b3be2396b12494f88fac39319de6f85
Source dataset
uspto-grants-2015_04
Patent number
US08999978B2

Reaction notes

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