Tetrahydrofuran → N-[5-[[5-(trifluoromethyl)furan-2-yl]methyl]-2,3-dihydro-1H-inden-2-yl]propane-2-sulfonamide

HRID 146541Notes

Reaction equation

HRID 146541 reaction equation
[Br:1][CH2:2][c:3]1[o:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:12][C:13]1([CH3:14])[C:15]([CH3:16])([CH3:17])[O:18][B:19]([c:20]2[cH:21][c:22]3[c:26]([cH:27][cH:28]2)[CH2:25][CH:24]([NH:29][S:30](=[O:31])(=[O:32])[CH:33]([CH3:34])[CH3:35])[CH2:23]3)[O:36]1>>[CH2:2]([c:3]1[o:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1)[c:20]1[cH:21][c:22]2[c:26]([cH:27][cH:28]1)[CH2:25][CH:24]([NH:29][S:30](=[O:31])(=[O:32])[CH:33]([CH3:34])[CH3:35])[CH2:23]2

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 27946052-(Bromomethyl)-5-(trifluoromethyl)furanHCID 46899971N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

Product 1

HCID 67088241N-[5-[[5-(trifluoromethyl)furan-2-yl]methyl]-2,3-dihydro-1H-inden-2-yl]propane-2-sulfonamide

Sources & evidence

ORD record
ord-8fc4ab8113d04a82a415930f14f4771f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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