反应详情

To a solution of [4-(chloromethyl)phenyl]methanol (4.691 g, 29.96 mmol) in toluene (30 ml) was added triphenylphosphine (9.444 g, 36.01 mmol). The mixture was heated under reflux for 20 hrs, and cooled to room temperature. The precipitate was collected by filtration, and dried under reduced pressure to give [4-(hydroxymethyl)benzyl](triphenyl)phosphonium chloride (11.47 g, yield 91.4%) as a white solid.

1. temperatureThe mixture was heated
2. temperatureunder reflux for 20 hrs
3. filtrationThe precipitate was collected by filtration
4. customdried under reduced pressure