HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86695588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86695587 | HCID 86695587 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86695588 | HCID 86695588 | 100% |
Reaction Steps
To (1S,5S)-8-tert-butyl 2-methyl 8-azabicyclo[3.2.1]octane-2,8-dicarboxylate (5.49 g) in EtOH (1 mL) was added 4M HCl in dioxane (5 mL). The reaction mixture was stirred at room temperature for 2 hours. Concentrated to give crude product (3.45 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999966B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-9d914a03d06e488b878c7d4b215b9bd6 |
| Source note | uspto-grants-2015_04 |