反应详情

tert-Butyl 4-(6-cyano-7-methylquinolin-2-yl)-3-oxopiperazine-1-carboxylate was treated with TFA (2 mL) and stirred for 20 minutes. Analysis of the reaction mixture by LC indicated that reaction had gone to completion. The solution was concentrated in vacuo and crude was azetroped (3×) with dichloroethane to furnish the title compound. LC/MS (IE, m/z): [M+1]+=267.

1. customAnalysis of the reaction mixture by LC indicated that reaction
2. concentrationThe solution was concentrated in vacuo and crude