反应详情

A flask charged with tert-Butyl 4-[2-{3-cyano-4-fluoro-2-methylphenyl}-2-oxoethyl]-3-oxopiperazine-1-carboxylate (0.030 g, 0.08 mmol) was treated with TFA (2.0 mL) for 20 minutes. Analysis of the reaction mixture by LC indicated that reaction had gone to completion. The solution was concentrated in vacuo and crude was co-evaporated with dichloroethane (3×8 mL) to furnish the title product. LC/MS (IE, m/z): [M+1]+=276.

1. customAnalysis of the reaction mixture by LC indicated that reaction
2. concentrationThe solution was concentrated in vacuo and crude