反应详情

To a solution of 4-(2-Hydroxyethyl)benzonitrile (0.38 g, 2.6 mmol) in DCM (5 mL) was added Dess-Martin reagent (1.7 g, 3.9 mmol). The mixture was allowed to stir at RT for 1 hour. TLC showed no starting material at that point. The reaction was diluted with DCM, worked up with Na2S2O3, washed with sodium bicarbonate, dried over sodium sulfate, and concentrated. The crude 4-(2-Oxoethyl)benzonitrile was used in the next step without further purification.

1. washwashed with sodium bicarbonate
2. dry with materialdried over sodium sulfate
3. concentrationconcentrated
4. customThe crude 4-(2-Oxoethyl)benzonitrile was used in the next step without further purification